Volume 1, Issue 1
Disease Prediction with a Maximum Entropy Method

Michael Shub, Qing Xu & Xiaohua Xuan

CSIAM Trans. Life Sci., 1 (2025), pp. 134-152.

Published online: 2025-03

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  • Abstract

In this paper, we propose a maximum entropy method for predicting disease risks. It is based on a patient’s medical history with diseases coded in International Classification of Diseases, tenth revision, which can be used in various cases. The complete algorithm with strict mathematical derivation is given. We also present experimental results on a medical dataset, demonstrating that our method performs well in predicting future disease risks and achieves an accuracy rate twice that of the traditional method. We also perform a comorbidity analysis to reveal the intrinsic relation of diseases.

  • AMS Subject Headings

00A69, 92B10

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COPYRIGHT: © Global Science Press

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@Article{CSIAM-LS-1-134, author = {Shub , MichaelXu , Qing and Xuan , Xiaohua}, title = {Disease Prediction with a Maximum Entropy Method}, journal = {CSIAM Transactions on Life Sciences}, year = {2025}, volume = {1}, number = {1}, pages = {134--152}, abstract = {

In this paper, we propose a maximum entropy method for predicting disease risks. It is based on a patient’s medical history with diseases coded in International Classification of Diseases, tenth revision, which can be used in various cases. The complete algorithm with strict mathematical derivation is given. We also present experimental results on a medical dataset, demonstrating that our method performs well in predicting future disease risks and achieves an accuracy rate twice that of the traditional method. We also perform a comorbidity analysis to reveal the intrinsic relation of diseases.

}, issn = {3006-2721}, doi = {https://doi.org/10.4208/csiam-ls.SO-2024-0004a}, url = {http://global-sci.org/intro/article_detail/csiam-ls/23913.html} }
TY - JOUR T1 - Disease Prediction with a Maximum Entropy Method AU - Shub , Michael AU - Xu , Qing AU - Xuan , Xiaohua JO - CSIAM Transactions on Life Sciences VL - 1 SP - 134 EP - 152 PY - 2025 DA - 2025/03 SN - 1 DO - http://doi.org/10.4208/csiam-ls.SO-2024-0004a UR - https://global-sci.org/intro/article_detail/csiam-ls/23913.html KW - Disease prediction, maximum entropy, bioinformatics. AB -

In this paper, we propose a maximum entropy method for predicting disease risks. It is based on a patient’s medical history with diseases coded in International Classification of Diseases, tenth revision, which can be used in various cases. The complete algorithm with strict mathematical derivation is given. We also present experimental results on a medical dataset, demonstrating that our method performs well in predicting future disease risks and achieves an accuracy rate twice that of the traditional method. We also perform a comorbidity analysis to reveal the intrinsic relation of diseases.

Shub , MichaelXu , Qing and Xuan , Xiaohua. (2025). Disease Prediction with a Maximum Entropy Method. CSIAM Transactions on Life Sciences. 1 (1). 134-152. doi:10.4208/csiam-ls.SO-2024-0004a
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